Article
A V141L polymorphism of the human LRMP gene is associated with survival of lung cancer patients.
Carcinogenesis - 1 Jul 2006
Manenti Giacomo, Galbiati Federica, Pettinicchio Angela, Spinola Monica, Piconese Silvia, Leoni Vera Piera, Conti Barbara, Ravagnani Fernando, Incarbone Matteo, Pastorino Ugo, Dragani Tommaso A
Abstract excerpt
Mouse Lrmp and Casc1 genes are candidates for the pulmonary adenoma susceptibility 1 (Pas1) locus, the major determinant of strain variation in lung tumor susceptibility. These genes contain coding and non-coding single nucleotide polymorphisms (SNPs) strongly associated with lung tumor risk in mice. Analysis of LRMP and CASC1 gene SNPs in 361 lung adenocarcinoma (ADCA) patients and 327 healthy controls revealed...
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