Article
Cyclic strain stimulates isoform-specific PKC activation and translocation in cultured human keratinocytes.
Journal of cellular biochemistry - 1 Dec 1997
Takei T, Han O, Ikeda M, Male P, Mills I, Sumpio B E
Abstract excerpt
Previous studies have demonstrated that cyclic strain induces keratinocyte proliferative and morphological changes. Since protein kinase C (PKC) is known to play an important role in the regulation of keratinocyte growth and differentiation, the objective of this study was to determine the role of the PKC signaling pathway as a mediator of strain modulation of the keratinocyte phenotype. In particular, we tested...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
