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Article

Frequency-dependent phenotype modulation of vascular smooth muscle cells under cyclic mechanical strain.

Journal of vascular research - 1 Jan 2007

Qu Ming-Juan, Liu Bo, Wang Han-Qin, Yan Zhi-Qiang, Shen Bao-Rong, Jiang Zong-Lai

Abstract excerpt

Phenotype transformation of vascular smooth muscle cells (VSMCs) is known to be modulated by mechanical strain. The present study was designed to investigate how different frequencies of mechanical strain affected VSMC phenotype. VSMCs were subjected to the strains of 10% elongation at 0, 0.5, 1 and 2 Hz for 24 h using a Flexercell strain unit. VSMC phenotype was assessed by cell morphology, measurement of...

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PMID: 17713348
DOI: 10.1159/000102278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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