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Article

Microgravity modifies protein kinase C isoform translocation in the human monocytic cell line U937 and human peripheral blood T‐cells

1 Jan 2002

Abstract excerpt

Individual protein kinase C (PKC) isoforms fulfill distinct roles in the regulation of the commitment to differentiation, cell cycle arrest, and apoptosis in both monocytes and T-cells. The human monocyte like cell line U937 and T-cells were exposed to microgravity, during spaceflight and the translocation (a critical step in PKC signaling) of individual isoforms to cell particulate fraction examined. PKC...

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PMID: 12210720
DOI: 10.1002/jcb.10273

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