Article
Polymorphic and tissue-specific imprinting of the human Wilms tumor gene, WT1.
The Japanese journal of human genetics - 1 Mar 1997
Nishiwaki K, Niikawa N, Ishikawa M
Abstract excerpt
We previously demonstrated maternal monoallelic expression of the Wilms tumor suppressor gene, WT1, in about half of pre-term placental villus and fetal brain tissues examined. There were two alternative explanations for this pattern of the WT1 expression, i.e., an imprinting polymorphism vs. a developmental stage-dependent switching from monoallelic to biallelic expression of the gene. To investigate these...
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