Polymorphic and tissue-specific imprinting of the human Wilms tumor gene, WT1.

doi:10.1007/BF02766923

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Article

Polymorphic and tissue-specific imprinting of the human Wilms tumor gene, WT1.

The Japanese journal of human genetics - 1 Mar 1997

Nishiwaki K, Niikawa N, Ishikawa M

Abstract excerpt

We previously demonstrated maternal monoallelic expression of the Wilms tumor suppressor gene, WT1, in about half of pre-term placental villus and fetal brain tissues examined. There were two alternative explanations for this pattern of the WT1 expression, i.e., an imprinting polymorphism vs. a d...

Topics

Alleles
Chorionic Villi
Female
Fetus
Gene Expression
Genes, Wilms Tumor
Genomic Imprinting
Humans
Organ Specificity
Polymorphism, Genetic
Pregnancy

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