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Article

Non-capacitative calcium entry in Chinese hamster ovary cells expressing the platelet-derived growth factor receptor.

The Journal of biological chemistry - 14 Nov 1997

Mathias R S, Zhang S J, Wilson E, Gardner P, Ives H E

Abstract excerpt

Platelet-derived growth factor (PDGF) is believed to produce intracellular calcium (Ca2+i) transients by inositol trisphosphate (InsP3)-mediated release of intracellular Ca2+ stores followed by "capacitative" Ca2+ entry due to emptying of these stores. We examined the roles for the phospholipase Cgamma-InsP3 pathway and the emptying of InsP3-dependent intracellular Ca2+ stores in PDGF-mediated Ca2+ entry....

Topics

Animals
CHO Cells
Calcium
Cricetinae
Heparin
Inositol 1,4,5-Trisphosphate
Microinjections
Mutation
Receptors, Platelet-Derived Growth Factor

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9360982
DOI: 10.1074/jbc.272.46.29076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9360982-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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