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Article

Requirement of a Src family kinase for initiating calcium release at fertilization in starfish eggs.

The Journal of biological chemistry - 8 Oct 1999

Giusti A F, Carroll D J, Abassi Y A, Terasaki M, Foltz K R, Jaffe L A

Abstract excerpt

Signal transduction leading to calcium release in echinoderm eggs at fertilization requires phospholipase Cgamma-mediated production of inositol trisphosphate (IP(3)), indicating that a tyrosine kinase is a likely upstream regulator. Because previous work has shown a fertilization-dependent association between the Src homology 2 (SH2) domains of phospholipase Cgamma and a Src family kinase, we examined whether a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10506191
DOI: 10.1074/jbc.274.41.29318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Requirement of a Src family kinase for initiating calcium release at fertilization in starfish eggs.PMID 10506191Read ↗

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Role of phospholipase Cγ at fertilization and during mitosis in sea urchin eggs and embryosSemantic proximity Read ↗

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