Article
Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis.
The Journal of investigative dermatology - 1 Apr 2000
Schaller M, Schackert C, Korting H C, Januschke E, Hube B
Abstract excerpt
Secreted aspartic proteinases (Saps) encoded by 10 genes of Candida albicans are important virulence factors for different types of candidiasis. Distinct SAP genes have previously been shown to contribute to tissue damage in a model of oral candidiasis. In this study a progressive SAP expression in the order SAP1 and SAP2 > SAP8 > SAP6 > SAP3 was observed in an in vitro model of cutaneous candidiasis based on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
