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Article

CCR5 and CXCR4 usage by non-clade B human immunodeficiency virus type 1 primary isolates.

Journal of virology - 1 Mar 2002

Thompson Daniah A D, Cormier Emmanuel G, Dragic Tatjana

Abstract excerpt

CCR5 and CXCR4 usage has been studied extensively with a variety of clade B human immunodeficiency virus type 1 (HIV-1) isolates. The determinants of CCR5 coreceptor function are remarkably consistent, with a region critical for fusion and entry located in the CCR5 amino-terminal domain (Nt). In particular, negatively charged amino acids and sulfated tyrosines in the Nt are essential for gp120 binding to CCR5....

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Source

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Identifiers

PMID: 11861874
DOI: 10.1128/jvi.76.6.3059-3064.2002
PMCID: PMC135972

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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