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Article

Differences in chemokine coreceptor usage between genetic subtypes of HIV-1.

Virology - 15 Feb 1998

Tscherning C, Alaeus A, Fredriksson R, Björndal A, Deng H, Littman D R, Fenyö E M, Albert J

Abstract excerpt

HIV-1 uses chemokine coreceptors for cell entry. CXCR4 is the major coreceptor for T-cell-line-adapted isolates and CCR5 for non-T-cell-line-adapted isolates. This study investigated if coreceptor usage differs between genetic subtypes of HIV-1. Eighty-one primary isolates representing nine different genetic subtypes (A-J, except I) were tested on U87.CD4 glioma cells stably expressing chemokine receptor CCR1,...

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Source

Identifiers

PMID: 9499793
DOI: 10.1006/viro.1997.8980

Genes

CXCR4
CCR5
CCR1
CCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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