Article
DNA sequence profile of TP53 gene mutations in childhood B-cell non-Hodgkin's lymphomas: prognostic implications.
European journal of haematology - 1 Aug 2003
Klumb Claudete Esteves, Furtado Daniel Rodrigues, de Resende Lídia Maria Magalhães, Carriço Maria Kadma, Coelho Arthur Moellman, de Meis Ernesto, Maia Raquel Ciuvalschi, Rumjanek Franklin David
Abstract excerpt
OBJECTIVES: The TP53 gene encodes a nuclear protein implicated in the regulation of the cell cycle, DNA repair, and apoptosis. TP53 mutations and other alterations have been described in numerous types of tumors, and some of these have been associated with poor prognosis. The aim of this study wa...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
