Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacology of delta2 glutamate receptors: effects of pentamidine and protons.

The Journal of pharmacology and experimental therapeutics - 1 May 2003

Williams Keith, Dattilo Michael, Sabado Thomas N, Kashiwagi Keiko, Igarashi Kazuei

Abstract excerpt

The properties of delta2 receptors, which have homology to glutamate receptors but are not gated by glutamate, were studied using the constitutively active Lurcher mutant delta2(A654T) expressed in Xenopus oocytes. The macroscopic current through delta2(A654T) channels in voltage-clamped oocytes was defined as the difference between the holding current measured in the presence of extracellular Na(+) and that in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholinesterase Inhibitors
Share to Membrane Potentials

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Neurologic Mutants

Share to Patch-Clamp Techniques

Share to Protons

Share to Receptors, AMPA

Share to Receptors, Glutamate

Share to Receptors, N-Methyl-D-Aspartate

Source

Identifiers

PMID: 12606689
DOI: 10.1124/jpet.102.045799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacology of delta2 glutamate receptors: effects of pentamidine and protons.PMID 12606689Read ↗

The delta subfamily of glutamate receptors: characterization of receptor chimeras and mutants.Semantic proximity Read ↗

Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg(2+)-insensitive mutants.Semantic proximity Read ↗

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.Semantic proximity Read ↗

Differential activation of individual subunits in heteromeric kainate receptors.Semantic proximity Read ↗

Molecular and functional diversity of the NMDA receptor channel.Semantic proximity Read ↗

Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue.Semantic proximity Read ↗

Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology.Semantic proximity Read ↗

What does it take to gate AMPA receptors?Semantic proximity Read ↗

Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.Semantic proximity Read ↗

Differential dependence on GluR2 expression of three characteristic features of AMPA receptors.Semantic proximity Read ↗

Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.Semantic proximity Read ↗

Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.