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Article

Transformation of rat inner medullary fibroblasts to myofibroblasts in vitro.

Kidney international - 1 Nov 1997

Grupp C, Lottermoser J, Cohen D I, Begher M, Franz H E, Müller G A

Abstract excerpt

Renal fibroblasts play a major role in the pathogenesis of renal interstitial fibrosis. This process is associated at least in some forms of interstitial fibrosis with a differentiation of fibroblasts into myofibroblasts, characterized by the de novo expression of alpha-smooth muscle (alpha-sm) actin and/or desmin. Both the mechanisms underlying this differentiation and their effects on cellular function are...

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Identifiers

PMID: 9350651
DOI: 10.1038/ki.1997.453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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