Article
An F-Box/WD40 repeat-containing protein important for Dictyostelium cell-type proportioning, slug behaviour, and culmination.
Developmental biology - 1 Aug 2000
Nelson M K, Clark A, Abe T, Nomura A, Yadava N, Funair C J, Jermyn K A, Mohanty S, Firtel R A, Williams J G
Abstract excerpt
FbxA is a novel member of a family of proteins that contain an F-box and WD40 repeats and that target specific proteins for degradation via proteasomes. In fruiting bodies formed from cells where the fbxA gene is disrupted (fbxA(-) cells), the spore mass fails to fully ascend the stalk. In additi...
Topics
- Amino Acid Motifs
- Amino Acid Sequence
- Ammonium Chloride
- Animals
- Blotting, Western
- Body Patterning
- Dictyostelium
- F-Box Proteins
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Molecular Sequence Data