Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography.

doi:10.1093/oxfordjournals.jbchem.a021782

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Article

Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography.

Journal of biochemistry - 1 Sept 1997

Ohmura T, Ueda T, Motoshima H, Tamura T, Imoto T

Abstract excerpt

His 15 of hen lysozyme is located at the protein surface and is partly buried by the neighboring residues. The side chain of His 15 forms hydrogen bonds with surrounding residues and these hydrogen bonds are somewhat buried. A series of mutant lysozymes at the position 15 (Gly, Ala, Val, and Phe)...

Topics

Animals
Chemical Phenomena
Chemistry, Physical
Chickens
Crystallography, X-Ray
Enzyme Stability
Guanidine
Muramidase
Mutation
Protein Conformation
Protein Denaturation
Protein Structure, Secondary
Protein Structure, Tertiary

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