Article
Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein.
Proteins - 15 Nov 2001
Takano K, Yamagata Y, Yutani K
Abstract excerpt
Our previous study of six non-Gly to Gly/Ala mutant human lysozymes in a left-handed helical region showed that only one non-Gly residue at a rigid site had unfavorable strain energy as compared with Gly at the same position (Takano et al., Proteins 2001; 44:233-243). To further examine the role of left-handed residues in the conformational stability of a protein, we constructed ten Gly to Ala mutant human...
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