Article
Distinguishing Plasmodium falciparum treatment failures from reinfections by restrictions fragment length polymorphism and polymerase chain reaction genotyping.
The American journal of tropical medicine and hygiene - 1 Oct 1997
Ohrt C, Mirabelli-Primdahl L, Karnasuta C, Chantakulkij S, Kain K C
Abstract excerpt
The inability to distinguish recrudescent Plasmodium falciparum infections (treatment failures) from reinfections (new infections) is an important impediment to the evaluation of antimalarial treatment regimens. Ten paired primary and recrudescent isolates collected near the Thai-Cambodian border...
Topics
- Adolescent
- Adult
- Animals
- Antimalarials
- DNA Fingerprinting
- Genotype
- Humans
- Malaria, Falciparum
- Male
- Military Personnel
- Plasmodium falciparum
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Recurrence
- Treatment Failure