Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recrudescence, Reinfection, or Relapse? A More Rigorous Framework to Assess Chloroquine Efficacy for Plasmodium vivax Malaria.

The Journal of infectious diseases - 7 Jan 2019

Popovici Jean, Pierce-Friedrich Lindsey, Kim Saorin, Bin Sophalai, Run Vorleak, Lek Dysoley, Hee Kim Hor Daryl, Lee Soon-U Lawrence, Cannon Matthew V, Serre David, Menard Didier

Abstract excerpt

Background: Plasmodium vivax resistance to chloroquine (CQ) has been reported worldwide, although the World Health Organization clinical drug efficacy studies protocol does not permit classification of patient outcomes. Methods: We enrolled 40 patients with P. vivax malaria in northeastern Cambodia, where >17% treatment failures were previously reported. Patients were treated with CQ (30 mg/kg) and followed for 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Cambodia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chloroquine

Share to Malaria, Vivax

Share to Plasmodium vivax

Share to Recurrence

Share to Treatment Failure

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 30102351
DOI: 10.1093/infdis/jiy484
PMCID: PMC6306015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recrudescence, Reinfection, or Relapse? A More Rigorous Framework to Assess Chloroquine Efficacy for Plasmodium vivax Malaria.PMID 30102351Read ↗

Frequent and genetically diverse Plasmodium vivax relapses contribute to malaria transmission in CambodiaSemantic proximity Read ↗

Genomic Analyses Reveal the Common Occurrence and Complexity of Plasmodium vivax Relapses in Cambodia.Semantic proximity Read ↗

Using Amplicon Deep Sequencing to Detect Genetic Signatures of Plasmodium vivax Relapse.Semantic proximity Read ↗

Therapeutic responses of Plasmodium vivax malaria to chloroquine and primaquine treatment in northeastern Myanmar.Semantic proximity Read ↗

High proportion of genome-wide homology and increased basal <i>pvcrt</i> levels in <i>Plasmodium vivax</i> late recurrences: a chloroquine therapeutic efficacy studySemantic proximity Read ↗

Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directionsSemantic proximity Read ↗

Estimation of the Antirelapse Efficacy of Tafenoquine, Using Plasmodium vivax Genotyping.Semantic proximity Read ↗

Individual Plasmodium vivax msp1 variants within polyclonal P. vivax infections display different propensities for relapse.Semantic proximity Read ↗

Influence of CYP2C8, CYP3A4, and CYP3A5 Host Genotypes on Early Recurrence of Plasmodium vivax.Semantic proximity Read ↗

Revisiting <i>Plasmodium vivax</i> molecular correctionSemantic proximity Read ↗

In vivo efficacy of artemether-lumefantrine and chloroquine against Plasmodium vivax: a randomized open label trial in central Ethiopia.Semantic proximity Read ↗

Genotyping methods to distinguish Plasmodium falciparum recrudescence from new infection for the assessment of antimalarial drug efficacy: an observational, single-centre, comparison study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.