Article
Distinguishing Plasmodium falciparum treatment failures from re-infections by using polymerase chain reaction genotyping in a holoendemic area in northeastern Tanzania.
The American journal of tropical medicine and hygiene - 1 Nov 2001
Magesa S M, Mdira K Y, Farnert A, Simonsen P E, Bygbjerg I C, Jakobsen P H
Abstract excerpt
An in vivo drug sensitivity study was conducted in Magoda village in northeastern Tanzania to evaluate the usefulness of polymerase chain reaction (PCR)-based genotyping of Plasmodium falciparum parasites to distinguish between re-infection and treatment failure. The study tested P. falciparum susceptibility to a combination of sulfadoxine/pyrimethamine (Fansidar; F. Hoffmann La Roche, Basel, Switzerland). Blood...
Topics
- Animals
- Child
- Child, Preschool
- Drug Resistance
- Genotype
- Humans
- Infant
- Malaria, Falciparum
- Plasmodium falciparum
- Polymerase Chain Reaction
- Tanzania