Molecular analysis of recrudescent parasites in a Plasmodium falciparum drug efficacy trial in Gabon

doi:10.1016/s0035-9203(97)90539-3

Article

Molecular analysis of recrudescent parasites in a Plasmodium falciparum drug efficacy trial in Gabon

1 Nov 1997

Abstract excerpt

Recrudescent Plasmodium falciparum parasites were sampled from 108 children taking part in a drug efficacy trial in Gabon. A finger-prick blood sample was taken from each child before treatment, and a post-treatment sample taken of the recrudescent parasites. Sample deoxyribonucleic acid was amplified by the polymerase chain reaction using primers specific to the P. falciparum antigen genes MSP-1, MSP-2 and...

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