Article
Relocation of Syk protein-tyrosine kinase to the actin filament network and subsequent association with Fak.
European journal of biochemistry - 15 Sept 1997
Sada K, Minami Y, Yamamura H
Abstract excerpt
Previous studies demonstrated that Syk protein-tyrosine kinase (Syk) is activated by thrombin in platelets. To elucidate the function of Syk in platelets, we have biochemically examined the intracellular location of Syk and the molecules associated with Syk, following platelet activation. In human platelets, thrombin induces the relocation of Syk to the cytoskeletal fraction presumably via Syk tyrosine...
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