Article
Beta 3 integrin phosphorylation is essential for Arp3 organization into leukocyte alpha V beta 3-vitronectin adhesion contacts.
Journal of cell science - 15 Mar 2004
Chandhoke Surjit K, Williams Matthew, Schaefer Erik, Zorn Linda, Blystone Scott D
Abstract excerpt
Integrins play a pivotal role in self-regulated hematopoietic adhesion and migration. Leukocyte alpha(V)beta(3) integrin-mediated adhesion to vitronectin requires protein kinase C activation and phosphorylation on tyrosine 747 of the beta(3) cytoplasmic tail. We have previously shown that beta(3)...
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