Article
A conserved family of WD-40 proteins binds to the retinoblastoma protein in both plants and animals.
The Plant cell - 1 Sept 1997
Ach R A, Taranto P, Gruissem W
Abstract excerpt
In mammalian cells, the retinoblastoma (RB) protein regulates G1 progression and functions through its association with various cellular proteins. Two closely related mammalian RB binding proteins, RbAp48 and RbAp46, share sequence homology with the Msi1 protein of yeast. MSI1 is a multicopy suppressor of a mutation in the IRA1 gene involved in the Ras-cAMP pathway that regulates cellular growth. Human RbAp48 is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
