Article
Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 1997
Kotanko P, Binder A, Tasker J, DeFreitas P, Kamdar S, Clark A J, Skrabal F, Caulfield M
Abstract excerpt
Populations of West African ancestry dwelling in Western communities exhibit greater prevalence of human essential hypertension and higher rates of end-organ damage. The sympathetic nervous system influences cardiac output, vascular tone, renal sodium reabsorption, and renin release and could be implicated in enhanced vascular responsiveness observed in African hypertensives. Such an effect could arise from...
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