Article
Association analysis of Arg16Gly polymorphism of the beta2-adrenergic receptor gene in offspring from hypertensive and normotensive families.
Blood pressure - 1 Jan 2002
Jindra A, Horký K, Peleska J, Jáchymová M, Bultas J, Umnerová V, Heller S, Hlubocká Z
Abstract excerpt
OBJECTIVE: Since beta2-adrenergic receptors (beta2AR) can influence blood pressure not only by vasodilation, but also participate in noradrenaline release from sympathetic nerve endings, we have studied whether Arg16Gly polymorphism of the beta2AR gene is associated with predisposition to essential hypertension and increased plasma noradrenaline concentration in offspring from normotensive (SN) and hypertensive...
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