Article
The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin.
American journal of hypertension - 1 Dec 2001
Ranade K, Shue W H, Hung Y J, Hsuing C A, Chiang F T, Pesich R, Hebert J, Olivier M, Chen Y D, Pratt R, Olshen R, Curb D, Botstein D, Risch N, Cox D R
Abstract excerpt
BACKGROUND: Several studies implicate polymorphisms in the human beta-adrenergic receptor gene (ADRB2) in the susceptibility to hypertension. We sought to replicate these results in a population of Chinese origin primarily from Taiwan and the San Francisco Bay area. METHODS: We genotyped >800 hypertensive subjects and individuals with low-normal blood pressure that were derived largely from the same families as...
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