Article
Suppressor analysis of mutations in the loop 2-3 motif of lactose permease: evidence that glycine-64 is an important residue for conformational changes.
Journal of bacteriology - 1 Apr 1997
Jessen-Marshall A E, Parker N J, Brooker R J
Abstract excerpt
A superfamily of transport proteins, which includes the lactose permease of Escherichia coli, contains a highly conserved motif, G-X-X-X-D/E-R/K-X-G-R/K-R/K, in the loops that connect transmembrane segments 2 and 3 and transmembrane segments 8 and 9. Previous analysis of this motif in the lactose...
Topics
- Amino Acid Sequence
- Biological Transport
- Cell Membrane
- Conserved Sequence
- DNA Mutational Analysis
- Escherichia coli
- Escherichia coli Proteins
- Glycine
- Kinetics
- Lactose
- Membrane Transport Proteins
- Monosaccharide Transport Proteins
- Phenotype
- Protein Conformation
- Suppression, Genetic
- Symporters