Article
Chromosome 19 single-locus and multilocus haplotype associations with multiple sclerosis. Evidence of a new susceptibility locus in Caucasian and Chinese patients.
JAMA - 15 Oct 1997
Barcellos L F, Thomson G, Carrington M, Schafer J, Begovich A B, Lin P, Xu X H, Min B Q, Marti D, Klitz W
Abstract excerpt
CONTEXT: Susceptibility to multiple sclerosis (MS) involves a genetically complex autoimmune component. However, except for genes in the HLA system, specific susceptibility loci are unknown or unconfirmed. OBJECTIVE: To investigate several loci spanning 3 candidate regions for a role in multiple sclerosis (MS) susceptibility in 2 ethnic groups using both single-locus and haplotype analyses. The 3 regions include...
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