Article
Multiple susceptibility loci for multiple sclerosis.
Human molecular genetics - 15 Sept 2002
Haines Jonathan L, Bradford Yuki, Garcia Melissa E, Reed Allison D, Neumeister Elizabeth, Pericak-Vance Margaret A, Rimmler Jacqueline B, Menold Marissa M, Martin Eden R, Oksenberg Jorge R, Barcellos Lisa F, Lincoln Robin, Hauser Stephen L
Abstract excerpt
Multiple sclerosis (MS) is a common and frequently disabling autoimmune disorder mediated by autoaggressive T cells and autoantibodies that target central nervous system myelin. While numerous studies have demonstrated a strong genetic component to MS, it has been difficult to identify the specific genes involved. Several genomic screens have been undertaken to locate such genes, but have not provided consistent...
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