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Article

Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis.

American journal of human genetics - 1 Mar 2002

Schmidt Silke, Barcellos Lisa F, DeSombre Karen, Rimmler Jacqueline B, Lincoln Robin R, Bucher Patricia, Saunders Ann M, Lai Eric, Martin Eden R, Vance Jeffery M, Oksenberg Jorge R, Hauser Stephen L, Pericak-Vance Margaret A, Haines Jonathan L

Abstract excerpt

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system, with a complex etiology that includes a strong genetic component. The contribution of the major histocompatibility complex (MHC) has been established in numerous genetic linkage and association studies. In addition to the MHC, the chromosome 19q13 region surrounding the apolipoprotein E (APOE) gene has shown consistent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11836653
DOI: 10.1086/339269
PMCID: PMC384947

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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