Article
Chromosome 19q13 and multiple sclerosis susceptibility in Finland: a linkage and two-stage association study.
Journal of neuroimmunology - 1 May 2002
Reunanen K, Finnilä S, Laaksonen M, Sumelahti M-L, Wikström J, Pastinen T, Kuokkanen S, Saarela J, Uimari P, Ruutiainen J, Ilonen J, Peltonen L, Tienari P J
Abstract excerpt
Several studies have previously provided some albeit weak evidence for linkage or association between chromosome 19q13 and multiple sclerosis (MS) susceptibility. We performed a two-stage association analysis with 19 markers spanning 7 Mb/5.5 cM of 19q13. In stage 1 analysis (135 MS families) allelic and haplotypic associations were found with markers within or close to the ApoE-ApoC subregion. These observations...
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