Article
Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44.
Genes and immunity - 1 Jan 2006
Kenealy S J, Herrel L A, Bradford Y, Schnetz-Boutaud N, Oksenberg J R, Hauser S L, Barcellos L F, Schmidt S, Gregory S G, Pericak-Vance M A, Haines J L
Abstract excerpt
Multiple sclerosis (MS) is a debilitating neuroimmunological and neurodegenerative disease with a strong genetic component. Numerous studies have failed to consistently identify genes that confer disease susceptibility except for association with HLA-DR. Seven non-HLA regions (1q, 2q, 9q, 13q, 16q, 18p and 19q) identified in a recent genomic screen were investigated by genotyping approximately 20...
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