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Article

Acetylator phenotype and genotype in patients infected with HIV: discordance between methods for phenotype determination and genotype.

Pharmacogenetics - 1 Mar 2000

O'Neil W M, Drobitch R K, MacArthur R D, Farrough M J, Doll M A, Fretland A J, Hein D W, Crane L R, Svensson C K

Abstract excerpt

The acetylator phenotype and genotype of AIDS patients, with and without an acute illness, was compared with that of healthy control subjects (30 per group). Two probe drugs, caffeine and dapsone, were used to determine the phenotype in the acutely ill cohort. Polymerase chain reaction amplification and restriction fragment length polymorphism analysis served to distinguish between the 26 known NAT2 alleles and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10762005
DOI: 10.1097/00008571-200003000-00009

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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