Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular biological characterization of an azole-resistant Candida glabrata isolate.

Antimicrobial agents and chemotherapy - 1 Oct 1997

Marichal P, Vanden Bossche H, Odds F C, Nobels G, Warnock D W, Timmerman V, Van Broeckhoven C, Fay S, Mose-Larsen P

Abstract excerpt

Two isolates of Candida glabrata, one susceptible and one resistant to azole antifungals, were previously shown to differ in quantity and activity of the cytochrome P-450 14alpha-lanosterol demethylase which is the target for azole antifungals. The resistant isolate also had a lower intracellular level of fluconazole, but not of ketoconazole or itraconazole, than the susceptible isolate. In the present study a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Probes

Share to Drug Resistance, Microbial

Share to Fungal Proteins

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9333053
DOI: 10.1128/AAC.41.10.2229
PMCID: PMC164098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular biological characterization of an azole-resistant Candida glabrata isolate.PMID 9333053Read ↗

Characterization of an azole-resistant Candida glabrata isolate.Semantic proximity Read ↗

Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients.Semantic proximity Read ↗

Mechanisms of azole resistance among clinical isolates of Candida glabrata in PolandSemantic proximity Read ↗

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatusSemantic proximity Read ↗

Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance.Semantic proximity Read ↗

Rapid, Transient Fluconazole Resistance in <i>Candida albicans</i> Is Associated with Increased mRNA Levels of <i>CDR</i>Semantic proximity Read ↗

Azole Resistance in Candida glabrata : Coordinate Upregulation of Multidrug Transporters and Evidence for a Pdr1-Like Transcription FactorSemantic proximity Read ↗

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virusSemantic proximity Read ↗

ERG11 mutations and expression of resistance genes in fluconazole-resistant Candida albicans isolates.Semantic proximity Read ↗

Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLPSemantic proximity Read ↗

Proteomic analysis of experimentally induced azole resistance in Candida glabrata.Semantic proximity Read ↗

Microarray and molecular analyses of the azole resistance mechanism in Candida glabrata oropharyngeal isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.