Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLP

2 Jan 2013

Abstract excerpt

BACKGROUND: Candida glabrata causes significant medical problems in immunocompromised patients. Many strains of this yeast are intrinsically resistant to azole antifungal agents, and treatment is problematic, leading to high morbidity and mortality rates in immunosuppressed individuals. The primary goal of this study was to investigate the genes involved in the drug resistance of clinical isolates of C. glabrata....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldose Reductase and Taurine
Share to Antifungal resistance and susceptibility
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23351326
DOI: 10.1186/2008-2231-21-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLPPMID 23351326Read ↗

Azole Resistance in Candida glabrata : Coordinate Upregulation of Multidrug Transporters and Evidence for a Pdr1-Like Transcription FactorSemantic proximity Read ↗

Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance.Semantic proximity Read ↗

Azole resistance in Candida glabrata clinical isolates from global surveillance is associated with efflux overexpressionSemantic proximity Read ↗

The evaluation of the overexpression of theERG‐11,MDR‐1,CDR‐1, andCDR‐2genes in fluconazole‐resistantCandida albicansisolated from Ahvazian cancer patients with oral candidiasisSemantic proximity Read ↗

Mechanisms of azole resistance among clinical isolates of Candida glabrata in PolandSemantic proximity Read ↗

Microarray and molecular analyses of the azole resistance mechanism in Candida glabrata oropharyngeal isolates.Semantic proximity Read ↗

Proteomic analysis of experimentally induced azole resistance in Candida glabrata.Semantic proximity Read ↗

Expression of ERG11 and efflux pump genes CDR1, CDR2 and SNQ2 in voriconazole susceptible and resistant Candida glabrata strainsSemantic proximity Read ↗

Molecular biological characterization of an azole-resistant Candida glabrata isolate.Semantic proximity Read ↗

Evaluation of Differential Gene Expression in Fluconazole-Susceptible and -Resistant Isolates of <i>Candida albicans</i> by cDNA Microarray AnalysisSemantic proximity Read ↗

Comparison of Gene Expression Profiles of Candida albicans Azole-Resistant Clinical Isolates and Laboratory Strains Exposed to Drugs Inducing Multidrug TransportersSemantic proximity Read ↗

The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.