Article
Characterization of an azole-resistant Candida glabrata isolate.
Antimicrobial agents and chemotherapy - 1 Dec 1992
vanden Bossche H, Marichal P, Odds F C, Le Jeune L, Coene M C
Abstract excerpt
A Candida (Torulopsis) glabrata strain (B57149) became resistant to fluconazole after a patient carrying the organism was treated with the drug at 400 mg once daily for 9 days. Growth of the pretreatment isolate (B57148) was inhibited by 50% with 0.67 microM ketoconazole, 1.0 microM itraconazole,...
Topics
- Antifungal Agents
- Azoles
- Candida
- Cytochrome P-450 Enzyme System
- Drug Resistance, Microbial
- Ergosterol
- Humans
- Microbial Sensitivity Tests
- NADPH-Ferrihemoprotein Reductase
- Phenotype
- Subcellular Fractions