Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus

10 Apr 2013

Abstract excerpt

OBJECTIVES: Recent increases in triazole resistance in Aspergillus fumigatus have been attributed primarily to target site (cyp51A) mutations. A recent survey of resistant isolates in Manchester showed that >50% of resistant isolates had no mutation in cyp51A or its promoter. We investigated the mechanisms of resistance in clinical azole-resistant isolates without cyp51A mutations. METHODS: Twelve azole-resistant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal and yeast genetics research
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23580559
DOI: 10.1093/jac/dkt075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatusPMID 23580559Read ↗

High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolatesSemantic proximity Read ↗

Azole resistance in Aspergillus fumigatus isolates from respiratory specimens in Lyon University Hospitals, France: prevalence and mechanisms involved.Semantic proximity Read ↗

Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus FungiSemantic proximity Read ↗

The TAC1 Gene in Candida albicans: Structure, Function, and Role in Azole Resistance: A Mini-Review.Semantic proximity Read ↗

Overexpression of Efflux Pump Genes is an Alternative Mechanism in Voriconazole Resistant Aspergillus fumigatus isolates Without Relative Mutations in CYP5A.Semantic proximity Read ↗

Examination of cyp51A and cyp51B expression level of the first Polish azole resistant clinical Aspergillus fumigatus isolateSemantic proximity Read ↗

Multiple mechanisms contribute to the development of clinically significant azole resistance in Aspergillus fumigatusSemantic proximity Read ↗

Multidrug resistance in fungi: regulation of transporter-encoding gene expressionSemantic proximity Read ↗

Exploring azole antifungal drug resistance in Aspergillus fumigatus with special reference to resistance mechanisms.Semantic proximity Read ↗

Azole resistance in Aspergillus fumigatus- comprehensive review.Semantic proximity Read ↗

Multidrug Transporters and Alterations in Sterol Biosynthesis Contribute to Azole Antifungal Resistance in Candida parapsilosis.Semantic proximity Read ↗

Investigation of Azole Resistance Involving cyp51A and cyp51B Genes in Clinical Aspergillus flavus Isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.