Article
Decreased retinal ganglion cell number and misdirected axon growth associated with fissure defects in Bst/+ mutant mice.
Investigative ophthalmology & visual science - 1 Sept 1997
Rice D S, Tang Q, Williams R W, Harris B S, Davisson M T, Goldowitz D
Abstract excerpt
PURPOSE: The autosomal semidominant mutation Bst (belly spot and tail) is often associated with small and atrophic optic nerves in adult mice and shares several important attributes with heritable optic nerve atrophy in humans. In this article, the authors present adult and developmental studies on the retinal phenotype in Bst/+ mice. METHODS: Retinal ganglion cells in adult Bst/+ mice were labeled retrogradely...
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