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Article

Genetic disruption of bassoon in two mutant mouse lines causes divergent retinal phenotypes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2021

Ryl Miriam, Urbasik Alexander, Gierke Kaspar, Babai Norbert, Joachimsthaler Anneka, Feigenspan Andreas, Frischknecht Renato, Stallwitz Nina, Fejtová Anna, Kremers Jan, von Wittgenstein Julia, Brandstätter Johann Helmut

Abstract excerpt

Bassoon (BSN) is a presynaptic cytomatrix protein ubiquitously present at chemical synapses of the central nervous system, where it regulates synaptic vesicle replenishment and organizes voltage-gated Ca2+ channels. In sensory photoreceptor synapses, BSN additionally plays a decisive role in anchoring the synaptic ribbon, a presynaptic organelle and functional extension of the active zone, to the presynaptic...

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Identifiers

PMID: 33811381
DOI: 10.1096/fj.202001962R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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