Article
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
Cancer research - 1 Oct 1997
Teng D H, Perry W L, Hogan J K, Baumgard M, Bell R, Berry S, Davis T, Frank D, Frye C, Hattier T, Hu R, Jammulapati S, Janecki T, Leavitt A, Mitchell J T, Pero R, Sexton D, Schroeder M, Su P H, Swedlund B, Kyriakis J M, Avruch J, Bartel P, Wong A K, Tavtigian S V
Abstract excerpt
Mitogen-activated protein kinases function in signal transduction pathways that are involved in controlling key cellular processes in many organisms. A mammalian member of this kinase family, MKK4/JNKK1/SEK1, has been reported to link upstream MEKK1 to downstream stress-activated protein kinase/JNK1 and p38 mitogen-activated protein kinase. This mitogen-activated protein kinase pathway has been implicated in the...
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