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MAP4K4 and cancer: ready for the main stage?

8 May 2023

Abstract excerpt

MAP4K4 is a serine/threonine kinase that belongs to the MAP kinase family and plays a critical role in embryogenesis and cellular migration. It contains approximately 1,200 amino acids and has a molecular mass of 140 kDa. MAP4K4 is expressed in most tissues where it has been examined and its knockout is embryonic lethal due to impaired somite development. Alterations in MAP4K4 function have a central role in the...

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PMID: 37223681
DOI: 10.3389/fonc.2023.1162835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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