Article
Mutation analyses of 268 candidate genes in human tumor cell lines.
Genomics - 15 Jun 2001
Teng D H, Chen Y, Lian L, Ha P C, Tavtigian S V, Wong A K
Abstract excerpt
We have performed a homozygous deletion screen on 268 candidate genes in 90 human tumor cell lines derived from multiple types of cancers. Most of the candidate genes investigated have been proposed to be involved in cellular processes that are germane to cancer progression, such as cell cycle control, genome maintenance, chromatin remodeling, cell adhesion, and apoptosis. We have detected novel homozygous...
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