Article
Image analysis of Feulgen-stained transformed NIH 3T3 cells differing in p21 expression and ras-induced metastatic ability.
Analytical and quantitative cytology and histology - 1 Apr 1994
Mello M L, Chambers A F
Abstract excerpt
Nuclear phenotypes of clonal and polyclonal T24 H-ras-transformed NIH 3T3 cells differing in p21 expression and experimental metastatic ability were studied in Feulgen-stained preparations by image analysis. The objective was to determine if these cells varied in their degree of chromatin condensation, as previously reported with cell transformation, or in any other chromatin texture property highlighted by image...
Topics
- 3T3 Cells
- Animals
- Cell Line, Transformed
- Cell Nucleus
- Cell Transformation, Neoplastic
- Chromatin
- DNA, Neoplasm
- Image Processing, Computer-Assisted
- Mice
- Mitotic Index
- Neoplasm Metastasis