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Article

Interactions between genetic predisposition and environmental toxicants for development of lung cancer.

Environmental and molecular mutagenesis - 1 Jan 1997

el-Zein R, Conforti-Froes N, Au W W

Abstract excerpt

Significant interindividual variations in health outcome may be caused by the inheritance of variant polymorphic genes, such as CYP2D6 and CYP2E1 for activation, and GSTM1 and GSTT1 for detoxification of chemicals. However, mechanistic studies linking the inheritance of predisposing genes with genotoxic effects towards cancer have yet to be systematically conducted. We have studied 54 lung cancer patients and 50...

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Source

Identifiers

PMID: 9329644
DOI: 10.1002/(sici)1098-2280(1997)30:2<196::aid-em12>3.0.co;2-8

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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