Article
Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis.
Hepatology (Baltimore, Md.) - 1 Feb 1997
Czaja A J, Strettell M D, Thomson L J, Santrach P J, Moore S B, Donaldson P T, Williams R
Abstract excerpt
Susceptibility for type 1 autoimmune hepatitis has been associated with the major histocompatibility alleles DRB1*0301, DRB3*0101, DRB1*0401, and DRB4*0103, whereas the DRB1*1501 allele may protect from the disease. Our aim was to determine if these alleles or others influence clinical manifestat...
Topics
- Adolescent
- Adrenal Cortex Hormones
- Adult
- Aged
- Alleles
- Antibodies, Antinuclear
- Autoimmune Diseases
- Disease Susceptibility
- Female
- Genes, MHC Class I
- Genes, MHC Class II
- HLA-DR Antigens
- Hepatitis
- Humans
- Male
- Middle Aged
- Muscle, Smooth
- Treatment Failure