Article
Genetic variation in factor VII associated with variation in plasma lipoprotein(a) concentration.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1997
Hegele R A, Breckenridge W C, Brunt J H, Connelly P W
Abstract excerpt
Cross-sectional and prospective studies have shown that individuals with high plasma lipoprotein(a) [Lp(a)] concentrations are at increased risk for coronary heart disease. Size polymorphism of the apolipoprotein(a) [apo(a)] glycoprotein accounts for approximately 35% of the variation in plasma L...
Topics
- Alleles
- Codon
- Factor VII
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Lipoprotein(a)
- Osmolar Concentration
- Phenotype