Article
Genetic variation in factor VII associated with variation in plasma lipoprotein(a) concentration.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1997
Hegele R A, Breckenridge W C, Brunt J H, Connelly P W
Abstract excerpt
Cross-sectional and prospective studies have shown that individuals with high plasma lipoprotein(a) [Lp(a)] concentrations are at increased risk for coronary heart disease. Size polymorphism of the apolipoprotein(a) [apo(a)] glycoprotein accounts for approximately 35% of the variation in plasma Lp(a) concentrations. However, there is no convincing evidence for associations between plasma Lp(a) and common genetic...
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