Article
Common genomic variation in the APOC3 promoter associated with variation in plasma lipoproteins.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997
Hegele R A, Connelly P W, Hanley A J, Sun F, Harris S B, Zinman B
Abstract excerpt
We hypothesized that common genomic variation that affected the expression and/or function of the products of the APOC3, APOE, FABP2, and PON1 genes would be associated with variation in biochemical phenotypes in a previously unstudied human sample. We determined genotypes of functional genomic v...
Topics
- Adolescent
- Adult
- Alleles
- Apolipoprotein C-III
- Apolipoproteins C
- Apolipoproteins E
- Arteriosclerosis
- Aryldialkylphosphatase
- Body Mass Index
- Carrier Proteins
- Cholesterol
- DNA Mutational Analysis
- Disease Susceptibility
- Esterases
- Fatty Acid-Binding Protein 7
- Fatty Acid-Binding Proteins
- Female
- Gene Frequency