Article
K-ras mutations and allelic loss at 5q and 18q in the development of human pancreatic cancers.
International journal of pancreatology : official journal of the International Association of Pancreatology - 1 Jun 1997
Sugio K, Molberg K, Albores-Saavedra J, Virmani A K, Kishimoto Y, Gazdar A F
Abstract excerpt
CONCLUSION: Our findings have implications for early diagnosis and for the identification of patients at increased risk. BACKGROUND: Invasive cancers of the pancreas frequently are preceded by and associated with a spectrum of preneoplastic changes. We investigate the presence of K-ras mutations and allelic loss at 5q and 18q loci in preneoplastic lesions associated with nine cases of invasive pancreatic ductal...
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