Article
Mutation status of K-ras, p53 and allelic losses at 9p and 18q are not prognostic markers in patients with pancreatic cancer.
Anticancer research - 1 May 2009
Salek Cyril, Minarikova Petra, Benesova Lucie, Nosek Vladimir, Strnad Robin, Zavoral Miroslav, Minarik Marek
Abstract excerpt
BACKGROUND: K-ras mutations and allelic losses of tumor suppressors p16 and DPC4 are perceived as potential markers for screening of pancreatic malignancy. In this study, molecular data is compared with survival statistics of the patients and whether they correlate with patients' prognosis is questioned. PATIENTS AND METHODS: Fifty three consecutive patients with advanced pancreatic cancer (stage III and IV) who...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
