Article
A treadmill exercise regimen for identifying cardiovascular phenotypes in transgenic mice.
The American journal of physiology - 1 Sept 1997
Fewell J G, Osinska H, Klevitsky R, Ng W, Sfyris G, Bahrehmand F, Robbins J
Abstract excerpt
Cardiovascular stress in response to treadmill exercise is frequently used to detect cardiac abnormalities that are not readily apparent at rest. Herein we describe a treadmill exercise protocol for mice that allows for quantitation of the performance of an animal and the ability to gather metabolic information in a nonrestraining manner using telemetry implant devices. Transgenic (TG) mice overexpressing...
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